James Sethna > Sloppy Models >
KaiC phosphorylation subnetwork
KaiC phosphorylation subnetwork
Code and data
- Model equations:
- Model parameters:
- Best-fit parameters: T =
25, 30,
35, All
- Parameter ensemble chosen to fit experimental data
(not yet equilibrated): T =
25, 30,
35, All
- Sensitivity analysis:
- Best-fit JtJ
(25,
30,
35,
All),
its eigenvalues
(25,
30,
35,
All),
and eigenvectors
(25,
30,
35,
All)
- Best-fit Hessian
(25,
30,
35,
All),
its eigenvalues
(25,
30,
35,
All),
and eigenvectors
(25,
30,
35,
All)
- Download all [tar.gz]
More information
- Paper from which the subnetwork was extracted:
Jeroen S. van Zon, David K. Lubensky, Pim R. H. Altena,
and Pieter Rein ten Wolde.
An allosteric model of circadian KaiC phosphorylation.
Proceedings of the National Academy of Sciences 104: 7420-7425.
- Paper with experimental data:
No Transcription-Translation Feedback in Circadian Rhythm
of KaiC Phosphorylation. Jun Tomita, Masato Nakajima,
Takao Kondo, and Hideo Iwasaki. Science 307, 251 (2005).
Model cartoon
Current ensemble fit to experimental data
Last modified May 19, 2008
Statistical Mechanics: Entropy, Order Parameters, and Complexity,
now available at
Oxford University Press
(USA,
Europe).