Segment polarity model

Code and data

• Model equations:
  • PDF
  • LaTeX
  • C
  • SBML (systems biology markup language)
• Model parameters:
  • "Perfect data" parameters
  • Parameter ensemble
• Sensitivity analysis:
  • "Perfect data" Hessian, its eigenvalues and eigenvectors
• Download all [tar.gz]

Notes

• The parameter ensemble was generated using using the cost function found in von Dassow's paper (see below for reference).
• The Hessian was generated by looking at changes in the dynatype of the chemical species that von Dassow et al. used in their cost function. Here we cannot compare with experimental data, so we use the "perfect data" Hessian, which assumes that the initial parameter values give a dynatype with zero residuals.

More information

• Original paper: von Dassow G, Meir E, Munro EM, Odell GM: The segment polarity network is a robust developmental module. Nature 2000, 406:188-192.

Statistical Mechanics: Entropy, Order Parameters, and Complexity, now available at Oxford University Press (USA, Europe).